Folinic acid therapy in cerebral folate deficiency: marked improvement in an adult patient.

Authors

Karin I1,2, Borggraefe I3, Catarino CB4,5, Kuhm C4,5, Hoertnagel K6, Biskup S6, Opladen T7, Blau N7, Heinen F3, Klopstock T4,5,8,9.
  1. Department of Neurology, Friedrich-Baur-Institute, University of Munich, Ziemssenstr. 1, 80336, Munich, Germany. Ivan.Karin@med.uni-muenchen.de.
  2. German Network for Mitochondrial Disorders (mitoNET), Munich, Germany. Ivan.Karin@med.uni-muenchen.de.
  3. Department of Pediatric Neurology, Developmental Medicine and Social Pediatrics, University of Munich, Munich, Germany.
  4. Department of Neurology, Friedrich-Baur-Institute, University of Munich, Ziemssenstr. 1, 80336, Munich, Germany.
  5. German Network for Mitochondrial Disorders (mitoNET), Munich, Germany.
  6. CeGaT GmbH, Center for Genomics and Transcriptomics, Tübingen, Germany.
  7. Division of Inborn Metabolic Diseases, University Children’s Hospital, Heidelberg, Germany.
  8. Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.
  9. DZNE-German Center for Neurodegenerative Diseases, Munich, Germany.