For the analysis, 3–5ml venous whole blood is required. The blood should be drawn into an EDTA Monovette® (purple top, EDTA tube) and spun lightly to avoid partial clotting. Label the Monovette with the patient’s full name, date of birth, and the date the blood was drawn.
By regular mail, please send the following items to our lab:
Isolated DNA samples may also be sent for analysis. The DNA sample should have 5 µg genomic DNA (concentration of at least 50 ng/µl in water or puffer). Label the sample tube with the patient’s full name and date of birth.
Declaration of Consent and Additional Documents
Please fill out the Order Form completely and send it together with your samples to ensure a rapid handling of the case.
NOTE: The signed declarations of consent of the patient (and the family members, if necessary) and the signature of the physician on the Order Form are very important.
Patients with private insurance or orders from foreign countries need an agreement to cover costs or the information that they need a quotation before.
Please note that any incomplete forms will delay the handling of your order.
This includes but is not limited to:
Incomplete order forms
Missing physician signature
Missing patient data
Missing letter of referral
Unsolved assumption of costs
Order Dried Blood Spot Kit
Dried Blood Spot Cards
Please follow these instructions for easy specimen shipping.
Complete the order form with the informed consent and signature of the patient.
Collect the blood sample from the patient. Use regular EDTA-blood tubes for collection, collect a minimum of 2 ml of blood. Mix well after obtaining the sample.
Transferring blood to spots
Prepare the blood cards on a clean, dry, and flat surface. Transfer 100 μl EDTA-blood sample in the middle of each of the ten spots on the two blood spot cards. Complete patient name, date of birth, and date of sample collection on both blood spot cards. If you are sending more than one patient (e.g. exome trio) use two cards for each patient. You can ship all samples for one cohort in one envelope.
Dry both blood spot cards at room temperature for at least two hours. When dried, cover the filter with the paper flap.
Please do not stack or cover the blood spot cards while drying. Drying with heat (e.g. hairdryers, heating, microwave, etc.) will damage the DNA. Do not store the filtercards in the refrigerator or freezer while drying.
Place both blood spot cards in the plastic protective sleeve for protection during transport. Remove the pink cover and close the plastic flap of the envelope.
Mail both blood spot cards and the order form(s) in the pre-addressed envelope to us.
Always send a signed consent order form with every sample.
Name and date of birth must be written on the order form and each dried blood spot card.
Always store the blood sport cards in a dry place at room temperature. Once the sample has dried, place the card in the plastic protective sleeve. In warm and humid climates, please send cards within one week.
Dried blood spot specimens are considered non-infectious, nonregulated, exempt materials by the U.S. Department of Transportation (DOT), the International Air Transporter Association (IATA), and the World Health Organizations (WHO). Local regulations and institutional policies must be adhered to.
Pipette 100 μl of required sample or approximately 4 drops onto the circle without touching the surface of the filter paper. The circle should be filled with blood. The entire circle should be uniformly saturated but the blood spots must not be connected.
Please avoid undersaturation or oversaturation of the card. Do not touch the surface of the filter paper.
How does it work?
Make a selection from the available tests. If you need help finding an appropriate test please contact our Diagnostic Support team.
Patient gets a genetic counseling and signs the Order Form with consent form.
Blood sample (3–5 ml purple top EDTA tube) or genomic DNA (5 μg) can be sent to us.