Panel for Tumor Syndromes

The enrichment of the coding regions and the adjacent intronic regions is performed using a in-solution hybridization technology. The selection of the targeted regions and the design of the enrichment baits is performed in-house.

High throughput sequencing is performed on Illumina platforms.
Bioinformatic processing of the data is achieved using an in-house computer cluster.

Following data processing, our team of scientists and specialists in human genetics analyze the data and issue a medical report.

• 1-2 ml EDTA blood or 1-2 µg genomic DNA
• Order form with declaration of consent according to German Genetic Diagnosis Act (GenDG)

Turnaround time: 4-6 weeks

The prices for our human genetic diagnostics depend on the size of the selected Diagnostic Panel and the selected gene sets. All prices include sequencing, bioinformatic analysis, and issuing of a medical report by our team of experts in human genetic diagnostics.

• Order form

The Panel for Tumor Syndromes contains the following genes.

• It is possible to select one or multiple predefined gene sets.
• In addition to the full analysis of the requested gene set(s), you may opt to expand the analysis to all genes of the Diagnostic Panel for variants that are pathogenic or likely pathogenic (ACMG class 4 and 5).
• If you would like to order a custom gene set, please contact us. We will support you throughout the ordering process.

Tumor Syndromes Panel gene directory:

AIP, AKT1, ALK, APC, ATM, ATR, AXIN2, BAP1, BARD1, BLM, BMPR1A, BRCA1, BRCA2, BRIP1, CCND1, CDC73, CDH1, CDK4, CDKN1B, CDKN1C, CDKN2A, CHEK2, CYLD, DDB2, DICER1, DIS3L2, EPCAM, ERCC1, ERCC2, ERCC3, ERCC4, ERCC5, FAM175A, FANCA, FANCB, FANCC, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCL, FANCM, FH, FLCN, GREM1, HNF1A, HNF1B, HOXB13, HRAS, IL1B, IL1RN, KIT, LIG4, LZTR1, MAD2L2, MAX, MC1R, MEN1, MET, MITF, MLH1, MRE11A, MSH2, MSH3, MSH6, MUTYH, NBN, NF1, NF2, NTHL1, PALB2, PALLD, PIK3CA, PMS2, POLD1, POLE, POLH, POT1, PRKAR1A, PRSS1, PTCH1, PTEN, RAD50, RAD51, RAD51C, RAD51D, RASAL1, RB1, RECQL4, RET, RHBDF2, RINT1, RNF43, RPS20, SCG5, SDHA, SDHAF2, SDHB, SDHC, SDHD, SEC23B, SLX4, SMAD4, SMARCA4, SMARCB1, SMARCE1, SPINK1, SPRED1, SRGAP1, STK11, SUFU, TMEM127, TP53, TSC1, TSC2, UBE2T, VHL, WRN, WT1, XPA, XPC, XRCC2, YAP1