Are Pathogenic Germline Variants in Metastatic Melanoma Associated with Resistance to Combined Immunotherapy?

Teresa Amaral 1,2, Martin Schulze 3, Tobias Sinnberg 1, Maike Nieser 3, Peter Martus 4, Florian Battke 5, Claus Garbe 1, Saskia Biskup 3,5, Andrea Forschner 1.
  1. Center for Dermatooncology, Department of Dermatology, University Hospital Tuebingen, Eberhard Karls University, 72076 Tuebingen, Germany.
  2. Portuguese Air Force, Health Care Direction, 1649-020 Lisbon, Portugal.
  3. Practice for Human Genetics, 72076 Tuebingen, Germany.
  4. Institute for Clinical Epidemiology and applied Biostatistics (IKEaB), Eberhard Karls University, 72076 Tuebingen, Germany.
  5. Center for Genomics and Transcriptomics (CeGaT) GmbH, 72076 Tuebingen, Germany.