News

31. January 2012 - B Braun takes an interest in CeGaT

B Braun Melsungen AG acquired a 20 % interest in CeGaT GmbH. With this investment B Braun for the first time enters the market for genetic diagnostics. B. Braun is a German based service provider for the health market with more than 43,000 employees and annual sales of EUR 4.4bn.The investment of B Braun gives CeGaT the opportunity to even further extend our range of Diagnostic Panels and to distribute them internationally.

16. January 2012 - New CeGaT-Panels

CeGaT introduced new Diagnostic Panels for Movements Disorders and Neurodegenerative Diseases:

  • Dystonia - 4 Sub-Panels, 27 genes
  • Neuroakanthocythosis - 1 Panel, 4 genes
  • Neurodegeneration with Brain Iron Accumulation (NBIA) - 1 Panel, 8 genes
  • Neuromuscular Diseases - approx. 500 genes, details to come

For further information, please visit the section Diagnostic Panels.

 

13. January 2012 - CeGaT invests in Ion Torrent

CeGaT just equipped its lab with an Ion Torrent Personal Genome Analyzer from Life Technologies. This brand new technology will be used for fast turn-around Diagnostic Panels and soon also for whole exome and transcriptome sequencing. Now CeGaT lab is equipped with a broad range of sequencing technologies and automized sample preparation ranging from two SOLiD 5500xl, over an Ion Torrent to a 96 capillary sequencer and Agilent BRAVO and EZ Bead systems.

 

27. October 2011 - Second SOLiD 5500xl

CeGaT increased its capacities of its Next-Generation-Sequencing facility. Our lab is now equipped with:

  • Two SOLiD 5500xl
  • Two SOLiD 4
  • Agilent BRAVO
  • Library Builder

This enables us to decipher up to 600 billion basepairs per week.

 

20. October 2011 - CeGaT Lab officially accredited

CeGaT is now officially accredited as Molecular Human Genetic Diagnostics Laboratory according to DIN EN ISO 15189:2007. Please have a look at the certificate from the German Accreditation Body.

 

15. October 2011 - CeGaT is Finalist for STEP Award 2011

Once again, CeGaT is nominated as finalists for one of the most prestigious awards for young and innovative companies. We are very proud to be among the finalists for the STEP Award 2011 presented by Hoechst Infraserv and F.A.Z. Institute.

 

30. September 2011 - CeGaT and Genomnia to cooperate on Italian market

CeGaT and Genomnia srl have signed an agreement for the promotion and distribution in Italy of sequencing-based diagnostic tests on Life Technologies' SOLiD machine for epilepsy and metabolic diseases, dementia, amyotrophic lateral sclerosis, Parkinson's disease, and hereditary eye diseases panels developed by CeGaT. Please see our joint press release.

 

28. June 2011 - CeGaT wins German Gründer Prize

CeGaT is the "Best German Start-Up Company 2011" and wins the most prestigious prize for entrepreneurs (Gründer) in Germany. The well-known Gründer Prize is promoted by Stern, Sparkasse, Porsche, and ZDF.

 Saskia Biskup (CEO) at the awarding in Berlin, 28. June 2011.

 

01. Juni 2011 - CeGaT upgrades its Epilepsy Panels

Based on the latest research further genes have been added to the existing Epilepsy panels. Furthermore we have introduced 6 new panels. We are now offering 20 Epilepsy panels with in total 327 genes:

  • Epilepsy Panel 1: Generalized / Myoclonic Epilepsy, Febrile Seizures, Absences (now 38 genes)
  • Epilepsy Panel 2: Epileptic Encephalopathies (now 30 genes) 
  • Epilepsy Panel 3: Epilepsy and X-linked Mental Retardation (now 25 genes)
  • Epilepsy Panel 4: CDG (Congenital Disorder of Glycosylation) Syndrome (now 23 genes)
  • Epilepsy Panel 5: Ceroidlipofuscinosis (now 8 genes)
  • Epilepsy Panel 6: Coenzyme Q Deficiency Syndrome (now 5 genes)
  • Epilepsy Panel 7: Joubert Syndrome (now 10 genes)
  • Epilepsy Panel 8: Selected Mitochondrial Disorders (now 35 nuclear encoded genes)
  • Epilepsy Panel 9: Lissencephaly and Polymicrogyria (now 18 genes)
  • Epilepsy Panel 10: Microcephaly and Pontocerebellar Hypoplasia (now 22 genes)
  • Epilepsy Panel 11: MPS and Mucolipidosis (now 15 genes)
  • new: Epilepsy Panel 12: Disorders of the Ras-MAPK Pathway (14 genes)
  • Epilepsy Panel 13: Walker-Warburg Syndrome (now 6 genes)
  • Epilepsy Panel 14: Zellweger Syndrome (now 9 genes)
  • Epilepsy Panel 15: Metabolic Disorders (now 50 genes)
  • new: Epilepsy Panel 16: Leukodystrophies (20 genes)
  • new: Epilepsy Panel 17: Migraine (6 genes)
  • new: Epilepsy Panel 18: Hyperekplexia (5 genes)
  • new: Epilepsy Panel 19: Holoprosencephaly (8 genes)
  • new: Epilepsy Panel 20: Neuronal Migration Disorders (31 genes)

Further information are available at Epilepsy Panels.

 

01. March 2011 - CeGaT upgrades to SOLiD 5500xl

Beginning of 2011 CeGaT has ordered the SOLiD 5500xl system. As official service provider of Applied Biosystems / life technologies we will be among the first using this technology. Per run we will be able to generate up to 180 Gb (= 180.000.000.000 bases). With the new nanobeads which will be available soon this output can be further increased up to approx. 300 Gb per run. The accuracy obtained is at more than 99.99%. Further information regarding the SOLiD 5500xl can be found at Applied Biosystems / life technologies.

 

20. December 2010 - New Retina Panels

CeGaT introduces three additional Diagnostic Panels for Hereditary Eye Diseases, namely:

  1. Stargardt disease and macular dystrophies (11 Gene)
  2. Cone rod dystrophies (25 Gene)
  3. Flecked retina disorders (6 Gene)

We are now offering 32 Diagnostic Panels. They are:

  • Dementia and ALS
    (1 Panel - 20 genes)
  • Parkinson Syndrome
    (1 Panel - 16 genes)
  • Epilepsy
    (15 Panels - 265 genes)
  • Hereditary Eye Diseases
    (15 Panels - 196 genes)

For further information please visit the section Diagnostic Panels.

 

14. November 2010 - Exome Sequencing and Nature Genetics

The group of Dr. Holger Prokisch, Institute of Human Genetics, Helmholtz Zentrum, Munich, Germany, was able to identify a new gene (ACAD9) as cause of complex I deficiency, a severe mitochondrial disorder. The gene was identified through Exome Sequencing performed at CeGaT GmbH.
Most interestingly, this study demonstrates how Exome Sequencing can contribute to finding the underlying gene and by this laying out the basis for functional experiments that can lead to new treatment options in so far undiagnosed cases.

Please see our full Press Release.

 

01. November 2010 - CeGaT offers Customized FISH Assays

Starting today, CeGaT together with Prof. Perner, Director of the Institute of Prostate Cancer Research, University Hospital of Bonn, offers the development of FISH assays for in-situ detection of amplifications, deletions, and translocations for nealy all gene loci, tailored to individual needs. Upon request we perform in-situ hybridisation on your material and the analysis of the experiments.

Further information are available at Customized FISH Assays.

 

26. October 2010 - CeGaT in GenomeWeb / InSequence

Today Monica Heger of GenomeWeb / InSequence published an article on CeGaT and its diagnostic panels. Please have a look at: CeGaT in GenomeWeb.

 

02. June 2010 - New Epilepsy Panels

CeGaT introduced 15 Epilepsy Panels in June 2010. With these Diagnostic Panels all genes associated with Epilepsy can be sequenced simultaneously on our SOLiD 4 platform. We offer a full Epilepsy Diagnostic (Sequencing on SOLiD 4 system, Data Analysis, Re-Sequencing of Variants, Report) for each of our panels.

We are now offering 28 Diagnostic Panels. They are:

  • Dementia and ALS
    (1 Panel - 20 genes)
  • Parkinson Syndrome
    (1 Panel - 16 genes)
  • Epilepsy
    (15 Panels - 238 genes)
  • Hereditary Eye Diseases
    (11 Panels - 168 genes)

For further information please go to: Diagnostic Panels

 

01. June 2010 - CeGaT Roadshow

The first CeGaT Roadshow will be held in Göttingen, Germany. On June 18, 2010, we will present applications and data for the SOLiD 4 technology together with Applied Biosystems / life technologies. Furthermore we will elaborate on our Diagnostic Panels recently introduced to the market.

The event is hosted by Prof. Nave, Director of the Department Neurogenetics, Max-Planck-Institute for Experimental Medicine. Please have a look at the attached Flyer with the agenda. If you are interested in joining this event, please send a short mail to roadshow@cegat.de.

 

28. May 2010 - Scientific Advisory Board: Prof. Dr. Peter Freisinger

CeGaT GmbH welcomes Prof. Dr. Peter Freisinger as a new member of the Scientific Advisory Board. Prof. Freisinger is the Physician-in-Chief of Pediatric Medicine in Reutlingen, Germany. He is specialized in metabolic and mitochondrial disorders, skeletal dysplasias, and neurodevelopmental diseases. Furthermore he has a focus on perinatal medicine in neonatology. Prof. Freisinger will consult CeGaT GmbH with respect to metabolic and mitochondrial diagostics.

 

May 2010 - Introduction of Diagnostic Panels!

CeGaT, Center for Genomics and Transcriptomics, is among the worldwide pioneers and the first German company introducing Diagnostic Panels. With our panels a high number of genes can be sequenced and diagnosed simultaneously. In total we offer 16 different panels, namely

  • Dementia and ALS
    (1 Panel, 20 Genes)
  • Parkinson Syndrome
    (1 Panel, 16 Genes)
  • Epilepsy
    (3 Panels - 55 Genes)
  • Hereditary Eye Diseases
    (11 Panels, 150 Genes)

» Diagnostic Panels

 

02. May 2010 - Price Dump for Exome and Transcriptome Sequencing!

Despite the introduction of the new SOLiD 4 Technology, CeGaT GmbH has reduced its prices for exome and transcriptome sequencing! For details go to Exome Sequencing and Transcriptome Sequencing or have a look at the attached Flyer.

 

30. April 2010 - SOLiD 4 Technology

CeGaT GmbH has upgraded its Next-Generation-Sequencing Facility to the latest available technology of ABI / life technologies. Now we are able to generate up to 100 billion base pairs per run. This means that the coverage per run has doubled and thus significantly more reads are generated for exome and transcriptome sequencing.

 

15. April 2010 - Scientific Advisory Board: Prof. Dr. Wolfgang Berger

CeGaT GmbH welcomes Prof. Dr. Wolfgang Berger as a new member of the Scientific Advisory Board. Prof. Berger is Director of the Institute of Medical Genetics, Division of Medical Molecular Genetics & Gene Diagnostics at University of Zurich. He will consult CeGaT GmbH with respect to genetic eye diseases and will coordinate the development of the retina-panels for Next Generation Sequencing together with Prof. Dr. Bernd Wissinger, Institute for Ophthalmic Research, University of Tübingen.

 

01. March 2010 - CeGaT strengthens its Team: Dr. Christian Wilhelm

CeGaT GmbH welcomes Christian Wilhelm, PhD, as new Director of Molecular Diagnostics. Dr. Wilhelm is highly knowledgeable with the techniques and methods of molecular diagnostics and will strengthen the CeGaT team with his long-lasting expertise.

 

14. September 2009 - Sequencing Software

CeGAT GmbH decides to introduce the SeqPilot from JSI Medisys as their sequencing software for DNA diagnostics.

 

31. August 2009 - CeGAT GmbH becomes official Service Provider of ABI

CeGAT is the only German company offering the SOLiD 3 Technology of Applied Biosystems (ABI) / life technologies. Since August 31, 2009, CeGAT has been an official service provider of ABI. The cooperation comprises all applications with regard to High-Throughput-Sequencing.